24 May '17, 11pm

Thanks for the interview @aamdsif

This study was first envisioned with just one cohort – a group of newly diagnosed severe aplastic anemia patients who received eltrombopag in combination with conventional IST (horse ATG and cyclosporine ). Eltrombopag was started two weeks after receiving ATG and starting cyclosporine to allow time to recover from the side effects of ATG. When we saw improvement in the complete overall response rate at six months, we used this observation to inform the treatment schedule for the subsequent cohort of patients. For the second cohort, we wondered if less eltrombopag could achieve the same result and stopped administering eltrombopag at three months. However, responses in the second cohort were lower and we determined that a longer treatment period of eltrombopag was needed and perhaps administered without delay. In the third cohort, participants started all three medications...

Full article: http://www.aamds.org/interview/eltrombopag-added-ist-yiel...

Tweets

Here's the link to the trial information:

aamds.org 23 May '17, 2pm

Cord blood unit(s) must be matched at a minimum of 4/6 to the recipient at HLA-A and B at low resolution using DNA-based t...

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aamds.org 28 May '17, 1pm

Your help makes it possible to meet patients' needs, hold impactful conferences, develop fresh education programs and fund...

DYK @aamdsif offers CME/CE as Grand Rounds and ...

aamds.org 15 May '17, 12pm

Program Summary The CME/CE-accredited MDS Rounds Program provides a forum for health care professionals who care for patie...

Family Camp 2017: Aplastic Anemia and Bone Marrow Failure Family Weekend | Aplastic Anemia and

Family Camp 2017: Aplastic Anemia and Bone Marr...

aamds.org 01 Jun '17, 12pm

We are proud to announce a new program we’ve developed in conjunction with The Hole in the Wall Gang Camp – the beloved or...