23 Apr '16, 3pm

How many people have asked you "So what exactly is PNH?" Here's the answer:

PNH is a rare and serious blood disease that causes red blood cells to break apart. Doctors call this breaking apart "hemolysis ". It happens because your blood cells are missing a protein that protects them from your body's immune system. When your red blood cells break apart, the hemoglobin inside them is released. Hemoglobin is the red part of red blood cells. Its job is to carry oxygen around your body. The release of hemoglobin causes most PNH symptoms. Hemolysis can put a patient at risk for serious health problems. A rare disease, the worldwide prevalence of PNH is estimated in the range of 1–5 cases per million, regardless of ethnicity. The disease can affect people of any age. It may be associated with aplastic anemia , myelodysplastic syndromes , or acute myelogenous leukemia . Where does the name come from? Here's where the name "paroxysmal nocturnal hemoglobinu...

Full article: http://aamds.org/about/pnh